What are the common causes of miscarriage?

　　Miscarriage is a very normal phenomenon, and girls nowadays feel that miscarriage is very common. What are the causes of miscarriage? Why do people also have miscarriages after being pregnant for a period of time? I will give you a good explanation of the causes of miscarriage and introduce the causes of the process.

　　The causes of spontaneous abortion include embryonic factors, maternal factors, paternal factors and environmental factors.

　　1. Embryonic factors : Embryonic chromosomal abnormalities are the main cause of miscarriage. Examination of offspring from early abortions reveals that 50%-60% have chromosomal abnormalities. Chromosomal abnormalities in either spouse can be passed on to offspring, leading to miscarriage. Chromosomal abnormalities include numerical abnormalities and structural abnormalities. In addition to genetic factors, adverse effects such as infection and drugs can also cause chromosomal abnormalities in offspring, and miscarriage often occurs before 12 weeks of pregnancy.

　　2. Maternal factors:

　　(1) Systemic disease : High fever can promote Uterus Contraction causes miscarriage, and infections such as Treponema pallidum, influenza virus, cytomegalovirus, mycoplasma, chlamydia, Toxoplasma gondii, and herpes simplex virus can cause fetus Chromosomal aberrations leading to miscarriage. Expectant mother suffers from heart failure, severe anemia Ischemic and hypoxic diseases such as hypertension, chronic nephritis and severe malnutrition can also lead to miscarriage.

　　(2) Endocrine abnormalities : Luteal corpus deficiency can lead to early miscarriage. Hypothyroidism, severe diabetes and uncontrolled blood sugar can also lead to miscarriage.

　　(3) Abnormal immune function : Immune factors related to miscarriage include the spouse's tissue compatibility antigen (HLA), fetal antigens, blood group antigens (ABO and Rh) and the mother's autoimmune status. The parents have the same HLA locus with high frequency, so insufficient maternal blocking antibodies can also lead to recurrent miscarriage. Blood type incompatibility between mother and child, excessive production of antiphospholipid antibodies in pregnant women, couple’s anti- sperm The presence of antibodies can cause the embryo or fetus to be rejected and cause miscarriage.

　　(4) Abnormal uterus : Deformed uterus such as uterine dysplasia, unicornuate uterus, double uterus, uterine septum, intrauterine adhesions, and submucosal or intramural uterine fibroids can affect the implantation and development of the embryo sac and lead to miscarriage. Severe cervical laceration, loose cervical os, and short cervix can lead to fetal rupture and miscarriage.

　　(5) Traumatic stimulation : Uterine trauma such as surgery, direct impact, and excessive sexual intercourse can also cause miscarriage; excessive stress, anxiety, fear, sadness and other mental trauma may also cause miscarriage.

　　(6) Bad habits : Excessive smoking, alcoholism, morphine, heroin and other drugs can cause miscarriage.

　　3. Father factor : Studies have confirmed that chromosomal abnormalities in sperm can lead to spontaneous abortion. but clinical There is no clear basis for whether the abnormally increased sperm abnormality rate is related to spontaneous abortion.

　　4. Environmental factors : Excessive exposure to arsenic, lead, formaldehyde, benzene, chloroprene, ethylene oxide and other chemical substances can also cause miscarriage.

　　There are many factors that lead to miscarriage. For example, the miscarriage mentioned above can cause female It will cause physical discomfort, and once a miscarriage occurs, it will cause great harm to the body. Only by paying attention to the causes of miscarriage and knowing what factors cause miscarriage can we avoid it in life.